Columbus, Ohio— October 28th InXite® Health Systems is excited to announce a partnership with the Ohio Attorney General’s Office, several leading hospitals in Ohio, and a leading genomic research company, Genemarkers, to identify the genetic factors that may contribute to a proclivity toward substance abuse disorders.

“Genetics and addiction often go hand-in-hand, but we need to find out how and translate this knowledge into clinical practice if we want to gain the upper hand in the battle against opioid addiction.” Ohio Attorney General Dave Yost said. “If we can prevent the problem, we can ultimately win the war.”

The study will be co-led by Dr. Jon Sprague, Director of Science and Research for the Attorney General’s Office and the Bureau of Criminal Investigation Eminent Scholar at Bowling Green State University, and Dr. Caroline Freiermuth, an Associate Professor of Emergency Medicine at the University of Cincinnati Medical Center. The study will recruit up to 1,500 emergency department patients at the University of Cincinnati and The Ohio State University. The specific goals of the study are to:

  • Determine which genetic markers are associated with the development of opioid use disorder.
  • Develop an Addiction Risk Score to better classify patient likelihood for future opioid use disorder.
  • Determine the prevalence of genetic markers associated with addiction risk in the general population.

Patients will be asked about factors associated with opioid addiction, including details of previous opioid exposure, current opioid use and other health history.

The research team will collect a cheek swab from each patient for DNA testing to determine the presence of 180 genetic markers suspected to be associated with opioid addiction. Samples of those with opioid use disorder will be compared to those without to determine which genetic markers are associated with opioid use disorder.

The study will leverage InXite Health System’s Patient-Centric, Value-Based Care Data Platform to collect sample data and genetic test results. InXite will provide researchers to perform the advanced machine learning algorithms processing to identify correlations between certain genetic markers and a disposition towards substance abuse. InXite will use data collected and analyzed by the genetic research team. The genetic research team is made up of scientists from The Ohio State University, the University of Cincinnati, Bowling Green State University and Case Western Reserve University. Genemarkers, a leader in genomic research based in Kalamazoo, Michigan, will provide scientists for analysis.

When InXite® Health Systems was founded in 2014, the idea of improving the healthcare system for all patients, providers, and payors throughout the country became the mission. The goal was to be able to provide a data platform that would house healthcare information in one central spot making healthcare access easy for the patient and those who care for them.

Historically, healthcare systems have centered around the payor and the provider. Payment was structured on the amount of services that a provider delivered, not on positive outcomes. For InXite® Health Systems, the patient always comes first and is always the focus. The core principle of InXite® Health Systems is to provide patient-centered, value-based care.

As the United States moves towards a system that is patient-centered, InXite® Health Systems sits poised on the cutting edge of technology offering solutions that are fast becoming major forces in modern healthcare.

InXite® Health Systems is dedicated to improving the health of the world, providing patient-centered software platform, reporting and analytics, and care services that connect all the parts of fragmented healthcare system. InXite® Health Systems provide data-driven insights that improve patient health outcomes, enhance satisfaction, and control health care costs.

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Christopher Stets Vice President of Marketing

614-408-1680 x5123

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Attorney General of Ohio Press Release

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